PhD Position in Molecular Modelling at the Medical University of Vienna, Austria

A PhD position is available immediately at the Medical University of Vienna, 
Institute of Pharmacology. The project focuses on neurotransmitter 
transporters function, substrate binding and quarternary structure using 
computational methods. Neurotransmitter molecules, released from the 
presynaptic neuron upon an electric stimulus, bind to receptors on the 
postsynaptic neuron, where they initiate an electrical response. 
Information in neurons is transmitted in pulses; therefore, fast clearance 
of neurotransmitter molecules is essential. Neurotransmitter transporters 
remove these signalling molecules by rapid uptake. The balance between 
release and uptake is crucial for normal brain function. Alteration can 
lead to neurological disorders including schizophrenia or depression.

During your PhD you will use molecular modelling and simulation methods to 
develop models of the neurotransmitter transporters within their 
physiological environment of nerve membranes and explore their function 
with atomic resolution. Furthermore, you will be studying the simulated 
processes in vitro by using biochemical and fluorescence spectroscopy 
methods.

Applicants must hold a master degree or equivalent and should have a 
background in computational methods. We are looking for a highly motivated 
candidate with a keen interest in our research topic. Our project is 
embedded in a multidisciplinary environment with a focus on 
neurotransmitter transporters (http://SFB35.at). In order to take 
advantage of the international environment we expect good communication 
skills, especially in English. 

Applications containing a cover letter, CV, copies of certificates and 
contact details of two references should be sent to:
harald.sitte=meduniwien.ac.at and thomas.stockner=meduniwien.ac.at

Prof. Harald H. Sitte & Dr. Thomas Stockner
Medical University Vienna 
Center for Physiology and Pharmacology
Institute of Pharmacology
Whringerstrasse 13A
1090 Vienna
http://www.meduniwien.ac.at/pharmakologie/stockner