PhD position on Molecular Simulation Studies of DNA-Damage and Repair
at Physics Department T38, Technical University Munich, Germany
A PhD position (funded by DFG:SFB749) is available in the Theoretical
Biophysics group (chair: Prof. Martin Zacharias) at Technical University
Munich to start immediately.
DNA molecules in cells are frequently damaged by radiation or chemical
modification. The recognition and repair of damaged DNA is of fundamental
importance for the survival of cells and for preventing transformation into
malignant (cancer) cells. Aim of the project is to elucidate the mechanism
of specific recognition of damaged DNA by repair enzymes at atomic detail
using molecular simulation techniques. The work involves molecular dynamics
simulations and advanced sampling applications as well as ligand-receptor
docking simulations. The computational work will be performed in close
collaboration with experimental groups in the area of structural biopolgy
and biophysics.
Successful candidates should have a diploma or master degree in either
physics, biophysics or physical chemistry combined with a strong interest
in (bio)molecular simulations. Experience with the Linux operating system
and a programming language is a plus.
The Technical University Munich belongs to the scientific top addresses
and is one of the nine Universities of Excellence in the Federal Republic
of Germany. State-of-the-art computer equipment is available. Please
contact Prof. Zacharias (martin.zacharias*o*ph.tum.de) or send your CV and
cover letter describing your research interests including the addresses
of two referees to:
Prof. Dr. Martin Zacharias
Chair of Theoretical Biophysics
Physics Department T38
Technical University Munich
James-Franck-Str. 1
D-85748 Garching, Germany
e-mail: Martin.Zacharias@ph.tum.de
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