Just learned about #PROTACs, a promising new class of drugs that target #protein degradation! Exciting times in the world of drug discovery. 🧪💊 https://t.co/kc3jsYoms5
— Girinath G. Pillai (@giribio) May 1, 2023
Don't be afraid to take risks and make mistakes. Learn it, Try it, Train it and Deploy it That's how we grow and learn in computational chemistry! #motivation #research #compchem #chemistry https://t.co/vEtB0medFR
— Girinath Pillai (@giribio) Apr 1, 2023
Species translation in protein structures refers to the process of aligning the amino acid sequences of two proteins from different species before performing molecular docking studies. https://t.co/4xUyVba2yC
— Girinath Pillai (@giribio) Mar 31, 2023
Insulin is a protein that is easily broken down by digestive enzymes in the stomach before it can be absorbed into the bloodstream. This makes it difficult for insulin to be absorbed effectively if it is taken orally, which is why it must be injected. #informative #researchideas https://t.co/gCkhm7LbU3
— Girinath Pillai (@giribio) Mar 27, 2023
Tautomers are different forms of a compound that exist in equilibrium with each other. They can affect the binding of a compound to a protein target because different tautomers have different chemical properties that can affect how well they interact with the protein. #medchem https://t.co/4c5bwIvA0S
— Girinath Pillai (@giribio) Mar 25, 2023
#UKQSAR interesting talks #data #ml #ai #compchem #drugdiscovery #cheminformatics #qsar #API https://t.co/IKGuskyrMV
— Girinath Pillai (@giribio) Mar 15, 2023
RT @NilsWeskamp: PostDoc opportunity at the interface of academia (Val Gillet, Sheffield) and industry: de novo design, chemical synthesis & evolutionary optimization. Please take a look or share: https://t.co/j9OqzAP5kA
— Girinath Pillai (@giribio) Mar 14, 2023
RT @MatthiasRarey: This years program of GRC Computer-Aided Drug Design Conference (Mt.Snow, July 16-21/23) just published: https://t.co/42NoAVXnnH
— Girinath Pillai (@giribio) Mar 9, 2023
Came across an interesting paper on Do's and Don'ts in generating #MachineLearning models & #data handling https://t.co/B9Wnh9N6X1 >Data >Models >Results>Visualization>Analysis >Deploy #ML #AI #Generative #Statistics #ArtificialIntelligence #DataScience #DataAnalytics #QSAR
— Girinath Pillai (@giribio) Mar 4, 2023
Future drug discovery would employ a lot of the following technologies: #AI & #ML #CRISPR gene editing #Quantum computing #Nanomedicine 3D printing VR & AR Synthetic biology Precision medicine Human #organoids #Blockchain technology #thread #drugdiscovery #genomics #pharma https://t.co/ghRo2VTS5X
— Girinath Pillai (@giribio) Mar 2, 2023
Insights on molecular dynamics Advancements in visualization techniques, allowing for the interactive exploration and analysis of molecular simulations. 1/6 #compchem #MD #biophysics #drugdiscovery https://t.co/HFLJsoX4V7
— Girinath Pillai (@giribio) Feb 20, 2023
10 steps to progress.... https://t.co/OAQNowGsja
— Girinath Pillai (@giribio) Feb 19, 2023
"A discovery in science, or a new theory, even when it appears most unitary and most all-embracing, deals with some immediate element of novelty or paradox within the framework of far vaster, unanalysed, unarticulated reserves of knowledge." - J. Robert Oppenheimer https://t.co/HCvQW2B8CV
— Girinath Pillai (@giribio) Feb 17, 2023
How can we improve the efficiency and accuracy of drug screening methods? #drugdiscovery #bioscience #pharma #pharmacology #futureofscience #research https://t.co/DK041LMmsO
— Girinath Pillai (@giribio) Feb 13, 2023
#Bard @Google 's #AI chatbot https://t.co/Cp3AYPLmA9 #ChatGPT Could we expect #ChemGPT? Something like #BioGPT.
— Girinath Pillai (@giribio) Feb 6, 2023
"The greatest reward in discovering a cure is not in financial gain, but in the healing and alleviation of suffering." - Paul Ehrlich https://t.co/M4NihUrrNP
— Girinath Pillai (@giribio) Feb 6, 2023
RT @D_B_McConnell: These were the 10 choices of BRD4 Chemical Matter that the students got for their assignment to design improved BRD4 Inhibitors. Which one would you choose? https://t.co/vYe8QPUVEr
— Girinath Pillai (@giribio) Feb 4, 2023
How can we improve the success rate of clinical trials and bring new drugs to market more quickly? Unanswered questions! #pharma #drugdiscovery #research #futureofscience https://t.co/xqHLQj6lr6
— Girinath Pillai (@giribio) Feb 3, 2023
RT @marcvanderkamp: #Postdoc position to do #compchem on #enzymes in my group @BristolBiochem! Want to explore using #ML potentials for enzyme reactions & simulation-led enzyme engineering? Apply by Feb 19th! https://t.co/wpSHotkCgR DM/email with Qs. (#BlackInSTEMM particularly encouraged)
— Girinath Pillai (@giribio) Feb 2, 2023
How can we better understand the complex mechanisms of drug action at the molecular level? Unanswered questions! #drugdiscovery #pharma #research #futureofbiology ##evolution https://t.co/Jk6Hb5cUpw
— Girinath Pillai (@giribio) Feb 1, 2023
