PhD fellowship in crystallography of G protein-coupled receptors

PhD fellowship in crystallography of G protein-coupled receptors

The Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen is pleased to announce that a PhD fellowship will be available from 1 October 2015 or soon thereafter in discussion with strongest applicant. The application deadline is 30 June 2015.

Applications are invited for the three-year fellowship from applicants who hold or expect to hold a master´s degree in a relevan…

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Drug Discovery Opportunities at D. E. Shaw Research

D. E. Shaw Research is seeking outstanding scientists with expertise in structure-based drug design or related areas to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment.

Areas relevant to our efforts include computer-aided drug design, fragment-based approaches, molecular modeling, chemo- and bioinformatics, medicinal chemistry, and target analysis and selection. Specific knowledge of an…

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Lab Head Medicinal Chemistry

The Strasbourg Access Platform has the mission to develop and advance a portfolio of innovative research projects from target validation to lead optimization supported by Sanofi Units/Divisions in partnership with academics or biotechs with the ultimate goal to enrich the global research program portfolio.

The Access Platform (54 scientists) covers high-throughput screening and automation, biochemistry and cell biology, drug design, bioinformatics, and medicinal chemistry capabilities.

T…

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Senior Scientist - Biochemistry

The Strasbourg Access Platform has the mission to develop and advance a portfolio of innovative research projects from target validation to lead optimization supported by Sanofi Units/Divisions in partnership with academics or biotechs with the ultimate goal to enrich the global research program portfolio.

The Access Platform (54 scientists) covers high-throughput screening, biochemistry and cell biology, drug design, and medicinal chemistry capabilities.

The Access Platform is opening a p…

via http://ift.tt/1puljGF

Senior Scientist - Biochemistry

The Strasbourg Access Platform has the mission to develop and advance a portfolio of innovative research projects from target validation to lead optimization supported by Sanofi Units/Divisions in partnership with academics or biotechs with the ultimate goal to enrich the global research program portfolio.

The Access Platform (54 scientists) covers high-throughput screening, biochemistry and cell biology, drug design, and medicinal chemistry capabilities.

The Access Platform is opening a p…

via http://ift.tt/1puljGF

Drug Discovery Opportunities at D. E. Shaw Research

D. E. Shaw Research is seeking outstanding scientists with expertise in structure-based drug design or related areas to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment.

Areas relevant to our efforts include computer-aided drug design, fragment-based approaches, molecular modeling, chemo- and bioinformatics, medicinal chemistry, and target analysis and selection. Specific knowledge of an…

via http://www.nature.com/naturejobs/science/jobs?escape=false&order_by=created_on

Medicinal Chemists

Medicinal Chemists

Salary: Competitive

Location: Cambridge

You have the passion and ability to use your chemistry expertise to deliver innovative drug design and synthesis contributions impacting the next generation of Oncology medicines. You have a Ph.D., Bachelor’s or Master’s degree in a chemistry-related discipline. What’s more, you’re driven to apply your talents in an industry-leading research environment. Consider this unique opportunity to join AstraZeneca’s Innovative Medicines and…

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Postdoc positions in Theoretical/Computational Biophysics Group

Theoretical and Computational Biophysics group at the Korea Institute for Advanced Study (KIAS) in Seoul, South Korea. Candidates are expected to have a background in physics, theoretical chemistry, or related quantitative sciences, with an ability to carry out both analytical and computational calculations and in particular a strong interest in biological questions.

Possible research topics include:

a) Application of polymer physics or soft matter physics idea to biological problems (e.g. genome/chromosome compaction, effects of molecular crowding, intrinsically disordered proteins)

b) Dynamics and function of biological nanomachines (transport motors, molecular chaperones, SNARE, ... etc) at single molecule level or their collective dynamics.  

c) Dynamics of nucleic acids (DNA, RNA), riboswitch, microRNA biogenesis, and RNA-mediated gene regulation.

d) Heterogeneous (Glassy) dynamics in biology.

e) Understanding molecular allostery through molecular simulations, bioinformatics, and network theory.

f) Understanding single molecule measurement data with theoretical and computational modeling.


The initial appointment for the position is for two years and is renewable for up to two additional years, depending on research performance. Those who are interested are encouraged to send a complete curriculum vitae with a cover letter, a list of publications, a research plan, and three letters of recommendation directly to Prof. Changbong Hyeon (e-mail : hyeoncb@kias.re.kr)

Postdoctoral and PhD positions in molecular simulations

Molecular simulation of co-solvent effects on macromolecules

Applications are invited for a postdoctoral fellowship in computational physical chemistry (Prof. Nico van der Vegt), Technische Universitt Darmstadt, Germany, starting date 1st August 2015. The proposed project deals with modeling co-solvent and specific ion effects on collapse/folding equilibria of water-soluble polymers and peptides by means of molecular simulations. The position is for one year, with possibility for renewal up to three years. Requirements for this position include: a PhD in an appropriate field, strong background in molecular simulation methods and statistical mechanics, excellent communication and organizational skills including excellent written and spoken English, programming skills, a desire and ability to work well in a team.

Applications including a statement of interest and curriculum vitae should be sent to vandervegt@csi.tu-darmstadt.de

Postdoc positions in Computational Materials Design

We are happy to announce multiple openings in the area of computational 
materials discovery and design. Postdoc positions are for a period of up 
to 3 years. Normal duration of a PhD is 3 years, of a Masters 
program  2 years. Successful candidates will develop and apply novel 
methods of computational materials discovery (ranging from optimization 
algorithms to machine learning and data mining). Newly developed methods 
will become part of our USPEX code (http://uspex.stonybrook.edu) and will 
be applied to problems ranging from physics of extreme conditions to 
biochemical studies, from energetic to electronic materials. Successful 
candidates will have solid background and a degree in at least one of 
these fields: physics, chemistry, materials science, biochemistry, Earth 
sciences, and programming skills are very desirable (though not necessary). 
 Interested candidates should send their curriculum vitae, a publication 
list, and reprints of a few selected publications to Prof. Artem R. Oganov
(a.r.oganov@mail.ru).




The positions are available immediately, and the starting date is 
negotiable. Applications will be accepted until the position is filled. 
Selected applicants will receive a highly competitive compensation 
package (salary commensurate with experience, qualifications and previous 
publication record, housing allowance in case relocation to Moscow will be 
needed, medical insurance). Excellent travel and computing support will be 
provided. For further information please contact Prof. Artem R. Oganov 
(a.r.oganov@mail.ru).




Skoltech
 Skolkovo Institute of Science and Technology (Skoltech) is a private 
graduate research university in Skolkovo, Moscow , Russia. Established in 
October 2011 in collaboration with MIT, Skoltech educates young leaders, 
advances scientific knowledge and fosters new technologies to address 
critical issues facing Russia and the world, Applying top international 
research and educational models, the university integrates the best Russian 
scientific traditions with twenty-first century entrepreneurship and 
innovation. By 2020, the postdoctoral community at Skoltech will grow to 
300 researchers in all the core areas of the institute. Skoltech is 
committed to diversity and opportunity, and application materials will be 
considered without regard to the gender, race, or nationality of the 
applicant.

Postdoc in MD simulations of biological membranes - Perth, Australia

The Biomolecular Modelling Group has an opening for a highly qualified 
post-doctoral research fellow in the use of molecular dynamics simulation 
techniques to investigate the effect of cryosolvents and sugar molecules 
on the structure and stability of biological membranes.

The position is available immediately for up to 2 years, with the 
possibility of further renewals upon mutual agreement and the availability 
of funding. The successful applicant will join an established research 
group comprising three Research Fellows, five PhD students and three 
undergraduate honours students. The group is headed by Professor Ricardo 
Mancera: 
https://health.curtin.edu.au/teaching/pharmacy_people.cfm/R.Mancera

The successful applicant will work on a multi-disciplinary and inter-
institutional research project funded by the Australian Research Council 
aimed at providing a molecular-level rationale of the factors that 
determine the ability of plant tissues to survive cryogenic storage, since 
the preservation of cell membrane structure is essential for the survival 
of tissues subjected to cryogenic storage at very low temperatures or 
dessication conditions. This molecular simulation study will run in 
parallel with biophysical experiments carried out at RMIT University 
(Melbourne) and cryogenic preservation studies carried out at the Botanic 
Gardens and Parks Authority of Western Australia (Perth).

Curtin University (http://www.curtin.edu.au) is the largest university in 
Western Australia and is ranked amongst the top universities in Australia 
and within the top 2% in the world. The Biomolecular Modelling Group has 
its own dedicated GPU cluster and is also one of the major users of the 
newly established Pawsey Centre, a national petaflop computing facility in 
Perth. In addition, living in the state capital Perth offers a great 
lifestyle due to Western Australia's superb weather, beaches and outdoors 
activities.

This position would suit someone with a PhD in molecular modelling or 
computational biophysics and a demonstrable successful track record in 
molecular dynamics simulations of biological systems. Preference will be 
given to candidates with experience in enhanced sampling methods and/or 
the simulation of biological membranes. Only applicants that fulfil these 
requirements need apply by submitting a copy of their full CV to Professor 
Ricardo Mancera (R.Mancera@curtin.edu.au), including full details of 
all academic degrees obtained, research skills and experience, 
publications and conference presentations, and the names of 2-3 referees.

Ph.D. Student Position - Gachon University, South Korea

An applicant must have master degree or close to receiving in the field of computer-aided drug design or informatics/computational chemistry. 
He/she must be self motivated, dedicated and passionate for the research. 
In addition, he/she must possess proof of English language proficiency. 
Familiarity with programming languages would be an advantage. 
An ideal candidate need to have background and interests in chemistry, biology and molecular modeling.
An ideal candidate can enjoy collaboration with synthetic chemists, biologists, and computer scientists 

Criteria:
The duration for completion of degree will be 4 years. 
In order to complete the degree, an applicant needs to publish more than 2 SCI/SCIE level research publications. 
Candidate can choose to work mote interesting among molecular modeling jobs. 

Resources: 
Linux (CENTOS, REDHAT) & window machines 
Schrodinger, Sybyl, OpenEye, Gromacs, Modeller, Knime, R

Interested candidates should contact me directly by email with their credentials:
- Cover letter explaining research interests and motivation
- A detailed CV mentioning English proficiency 
- Publication details, if any
- Scanned copies of transcript and all other documents
- Skype based interview or direct meeting if an applicant is in Korea.
- Applicants with MS can have research experience in Korea before entrance

Contact
Kim Mi-hyun, Ph.D
Assistant Professor at 
College of Pharmacy, Gachon University, 
155 Gaetbeol-ro, Yeonsu-gu, Incheon city, 406-840, South Korea
Email; kmh0515@gachon.ac.kr

PhD in Computational studies - UIC, Chicago

Applications are invited for PhD studies in theoretical physical chemistry 
focused on computational modeling of nanoscale systems with physical, 
chemical, and biological origins. Most research projects are done in 
close collaborations with top experimentalists. Possible research 
projects are: 1) electronic structure and transport calculations in 
functionalized layered nanomaterials, 2) classical and quantum molecular 
dynamics simulations of individual colloidal nanoparticles with active 
ligands, 3) multiscale simulations of the self-assembly of nanoparticles 
and structural analysis of the formed meta-material. The research will 
be conducted in the group of Prof. Petr Kral in the Chemistry Department 
of the University of Illinois at Chicago (http://www2.chem.uic.edu/pkral/).  

We are seeking creative and highly motivated individuals, with computational 
skills and background in physics, chemistry, or biology. Preliminary 
knowledge of computational methods used in the above fields is very welcome, 
i.e. methods used in electronic structure calculations, quantum transport, 
molecular dynamics, etc. The candidates should be interested to conduct 
interdisciplinary theoretical research at the nanoscale. Our graduate 
students publish their results in top journals and continue with their 
postdoctoral research at the best US institutions.

Interested candidates should send e-mail their CV and the names and contact 
information of several references to: pkral@uic.edu